You’ve seen this loop.
Symptoms don’t improve.
So the dose gets adjusted.
When that doesn’t work,
new ratios get invented.
Estrogen gets pushed higher.
Protocols get more complicated.
And when none of it helps?
Too often, the patient gets blamed.
“Non-compliant.”
“Didn’t do it right.”
“Didn’t give it enough time.”
Let’s be honest.
That’s not precision medicine.
That’s guessing.
Throwing darts in the dark
and hoping something sticks.
Real medicine doesn’t guess.
It understands where hormones act,
how they accumulate,
and why symptoms don’t always match labs.
If the model is wrong,
no amount of tweaking the numbers will fix it.
