Postpartum Depression: What Happens When Progesterone Falls?

What really happens to a woman’s hormones after childbirth?
During pregnancy, progesterone rises for months. After delivery, those hormone levels fall rapidly, and the brain has to adjust to a major biological shift.
In this video, Dr. Taylor explores the connection between progesterone, allopregnanolone (allo), and GABA, and why women may respond differently to similar postpartum hormone changes.
The key question isn’t only how much progesterone is present—it may also matter what the body does with progesterone and how the brain responds when those levels change.
Learn more about the science behind postpartum hormonal changes, brain adaptation, and why one hormone measurement may not tell the whole story.
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